Pathobiology of cardiac dyssynchrony and resynchronization
نویسندگان
چکیده
منابع مشابه
Echocardiography, dyssynchrony, and the response to cardiac resynchronization therapy.
Biventricular pacing or cardiac resynchronization therapy (CRT) has been a considerable advance in the therapy of chronic heart failure. However, it is clear that not all patients benefit either in terms of symptoms or cardiac function, and some may be worsened by CRT. In this review, we consider the arguments, both clinical and economical, in favour of improved selection of patients for CRT ot...
متن کاملDyssynchrony, contractile function, and response to cardiac resynchronization therapy.
BACKGROUND Despite benefits of cardiac resynchronization therapy (CRT) in patients with severe but less symptomatic heart failure, approximately 30% of patients do not fully respond to treatment. We hypothesized that a combined assessment of left ventricular (LV) dyssynchrony and contractile function by strain-based imaging would identify patients who would most benefit from CRT. METHODS AND ...
متن کاملUsefulness of left ventricle dyssynchrony assessment before cardiac resynchronization implantation.
BACKGROUND A number of trials have demonstrated the effect of cardiac resynchronization therapy (CRT) on functional improvement and reversed left ventricle remodeling. Meeting contemporary guidelines approximately 30- 40% of patients do not respond to CRT (non-responders). AIM To quantify the predictive ability of basal QRS width and basal echocardiographic parameters of left ventricle contra...
متن کاملSelecting patients for cardiac resynchronization therapy: electrical or mechanical dyssynchrony?
Cardiac resynchronization therapy (CRT) markedly reduces morbidity and mortality in patients with heart failure and prolonged QRS duration. Landmark trials have included over 4000 patients based on their electrocardiogram. A few small, observational, non-randomized, single centre studies of short duration have suggested that echocardiographic measurement of mechanical dyssynchrony may better id...
متن کاملImprovement in left ventricular intrinsic dyssynchrony with cardiac resynchronization therapy
OBJECTIVE Cardiac resynchronization therapy (CRT) has been shown to induce a structural and electrical remodeling; the data on whether left ventricle (LV) reverse remodeling is associated with restitution of intrinsic contraction pattern are unknown. In this study, we investigated the presence of improvement in left ventricular intrinsic dyssynchrony in patients with CRT. METHODS A total of 4...
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ژورنال
عنوان ژورنال: Heart Rhythm
سال: 2009
ISSN: 1547-5271
DOI: 10.1016/j.hrthm.2009.08.017